Construction and veri cation of a novel prognostic risk model for kidney renal clear cell carcinoma based on immunity-related genes

HIGHLIGHTS

SUMMARY

    In total, the expression profiles of 2,483 immunity-related genes were retrieved, with the complete gene names obtained from the Immunology Database and Analysis Portal (ImmPort) database`s Gene List module (Supplementary Table S1). Since immune-associated genes (IAGs) are known to significantly influence the onset and progression of KIRC, (Ghatalia et_al, 2019; Xu et_al, 2019), several types of immunotherapies, including the use of programmed death-1 (PD-1) inhibitors, cytotoxic T-lymphocyte associated protein 4 (CTLA-4) inhibitors, or programmed deathligand 1 (PD-L1) inhibitors, are proving to be effective treatment options . . .

     

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