Prognostic significance of the cxcls and its impact on the immune microenvironment in ovarian cancer

HIGHLIGHTS

SUMMARY

    Ovarian cancer (OC) is the most common type of cancer in the female reproductive system and the fifth most common cause of cancer-related death in women worldwide. The TME consists of tumor cells and nontumor cells, such as B cells, CD4+T_cells, CD8+T_cells, macrophages, neutrophils, and dendritic cells. There is growing evidence that the presence of innate immune cells (macrophages, neutrophils, dendritic cells, etc.) as well as adaptive immune cells (T and B cells) in the tumor microenvironment (TME) contributes to tumor progression. The heterogeneity of tumor is not only determined by . . .

     

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