Optimizing antidotal treatment with the oral hsp90 inhibitor tas-116 against hydrochloric acid-induced pulmonary fi brosis in mice

HIGHLIGHTS

  • who: Hsp and collaborators from the University of Kansas Medical Center, United States have published the Article: Optimizing antidotal treatment with the oral HSP90 inhibitor TAS-116 against hydrochloric acid-induced pulmonary fi brosis in mice, in the Journal: (JOURNAL) of 15/03/2022
  • what: The authors investigated the optimal dosing and windows of administration of TAS-116 against HCl-induced pulmonary fibrosis and chronic lung injury in mice. The authors used three different doses in search of the minimal effective dose against HCl-challenged animals showed a decrease in pressurevolume (PV) loops . The authors . . .

     

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