Construction of fusion protein for enhanced small rna loading to extracellular vesicles

HIGHLIGHTS

  • who: Masoumeh Es-Haghi et al. from the AIVirtanen Institute for Molecular Sciences, University of Eastern Finland, Yliopistonranta E have published the research: Construction of Fusion Protein for Enhanced Small RNA Loading to Extracellular Vesicles, in the Journal: Genes 2023, 14, x FOR PEER REVIEW of /2023/
  • what: The authors developed fusion protein of EV membrane protein and RNA-binding protein (hCD9.hAGO2). The authors show that the EVs engineered with hCD9.hAGO2 contain significantly higher levels of miRNA or shRNA (miR-466c or shRNA-451 respectively) compared to EVs that are isolated from cells . . .

     

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