Rational design of potent ultrashort antimicrobial peptides with programmable assembly into nanostructured hydrogels

HIGHLIGHTS

  • who: January et al. from the The University of Melbourne, Australia have published the research: Rational design of potent ultrashort antimicrobial peptides with programmable assembly into nanostructured hydrogels, in the Journal: (JOURNAL)
  • what: The authors report the bi-functional rational design of Fmoctetrapeptides for potent antimicrobial activity and control of peptide hydrogelation through molecular self-assembly. To test the influence of backbone conformation in the approach , the authors designed a second peptide, P-Priscilicidin that includes a proline turn to disrupt backbone linearity and potentially peptide self-assembly.
  • how: Using a large set . . .

     

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