Ackr3 promotes cxcl12/cxcr4-mediated cell-to-cell-induced lymphoma migration through ltb4 production

HIGHLIGHTS

  • who: Paola Antonello and collaborators from the University of Brescia, Italy have published the research: ACKR3 promotes CXCL12/CXCR4-mediated cell-to-cell-induced lymphoma migration through LTB4 production, in the Journal: (JOURNAL)
  • what: The authors demonstrate that in the presence of CXCL12 wild_type VAL cells (VAL-wt), which can express ACKR3 on the cell surface, create cues that in_vitro can be sensed by CXCR4+ follower VAL-wt. Using a novel computational analysis of 3D migration, the authors show that in the presence of CXCL12 VAL-wt stimulate cell-to-cell-induced migration presumably through . . .

     

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