Case report: somatic mutations in microtubule dynamics-associated genes in patients with wnt-medulloblastoma tumors

HIGHLIGHTS

  • who: Rostislav Skitchenko from the AORN Santobono-Pausilipon, Italy University of Toronto, Canada have published the research: Case report: Somatic mutations in microtubule dynamics-associated genes in patients with WNT-medulloblastoma tumors, in the Journal: (JOURNAL)
  • what: Initially, the authors focused the analysis on missense variants and protein truncating variants (PTV).
  • how: The authors used COSMIC and PeCan focused on pediatric oncology.

SUMMARY

    Most cases (~70%) of MB Frontiers in Oncology frontiersin.org 10.3389/fonc.2022.1085947 proliferation activity along with synaptophysin expression, which is used to distinguish . . .

     

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