HIGHLIGHTS
- who: Michael J. Gilhooley from the LaboratoryUniversity of have published the Article: A systematic comparison of optogenetic approaches to visual restoration, in the Journal: (JOURNAL) of 25/06/2022
- what: In this study the aim was to compare two optogenetic tools: mammalian melanopsin (hOPN4) and microbial red-shifted channelrhodopsin (ReaChR) expressed within two subpopulations of surviving cells in a degenerate retina. The authors show that targeting different cell groups markedly alters the reconstituted light responses. The authors demonstrate the use of the compressed L7-6 promoter construct to deliver a gene (hOPN4) specifically to a . . .
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