Design, synthesis and pharmacological evaluation of new quinoline-based panx-1 channel blockers

HIGHLIGHTS

  • who: Letizia Crocetti and colleagues from the Neurofarba, Pharmaceutical and Nutraceutical Section, University of Florence, Via Ugo Schiff, Sesto Fiorentino, Italy have published the article: Design, Synthesis and Pharmacological Evaluation of New Quinoline-Based Panx-1 Channel Blockers, in the Journal: (JOURNAL)
  • what: In this study as a continuation of the research in this field the authors report the design and evaluation of new quinoline-based Panx-1 blockers. By considering the measure errors and that the highest incubation time involved in the study was 120 min, the t1/2 parameter of compounds with a . . .

     

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