Preparation and physiochemical analysis of novel ciprofloxacin / dicarboxylic acid salts

HIGHLIGHTS

  • who: Thomas Hibbard from the School of Pharmacy, University of Reading, Reading, AD, UK have published the article: Preparation and Physiochemical Analysis of Novel Ciprofloxacin / Dicarboxylic Acid Salts, in the Journal: (JOURNAL)
  • what: Crystalline CFX salts with distinct physicochemical properties have been successfully produced by ball milling and solution crystallization.

SUMMARY

    Aqueous solubility of active_pharmaceutical_ingredients (APIs) can be improved through the discovery of new solid forms. The measured solubilities, starting from each of the CFX salts, are substantially greater than the measured solubility starting from CFX base. An examination by PXRD . . .

     

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