Alphafold2-multimer guided high-accuracy prediction of typical and atypical atg8-binding motifs

HIGHLIGHTS

• who: Tarhan Ibrahim and colleagues from the Agrotechnology and Food, Biochemistry, Wageningen University and Research, Wageningen, the Netherlands, INGEBI-CONICET, Ciudad Autonoma de Buenos Aires, Buenos Aires, Argentina have published the research: AlphaFold2-multimer guided high-accuracy prediction of typical and atypical ATG8-binding motifs, in the Journal: (JOURNAL)
• what: The authors show that protein modelling using Alphafold-Multimer (AF2-multimer) identifies both canonical and atypical AIM/LIR motifs with a high level of accuracy. By combining protein modelling from AF2-multimer with phylogenetic analysis of protein sequences and protein-protein interaction assays the authors . . .
  

   

  

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