Can metformin relieve tibiofemoral cartilage volume loss and knee symptoms in overweight knee osteoarthritis patients? study protocol for a randomized, double-blind, and placebo-controlled trial

HIGHLIGHTS

  • who: Guangfeng Ruan from the Clinical Research Centre, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China have published the research: Can metformin relieve tibiofemoral cartilage volume loss and knee symptoms in overweight knee osteoarthritis patients? Study protocol for a randomized, double-blind, and placebo-controlled trial, in the Journal: (JOURNAL)
  • what: The authors purpose to conduct a randomized, double-blind, and placebo-controlled trial to examine the structure-modifying and symptom-relieving effects of metformin on knee OA. Withdrawal If participants withdraw from the study before the end of the trial, the reason and date . . .

     

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