Utility of monocyte hla-dr and rationale for therapeutic gm-csf in sepsis immunoparalysis

HIGHLIGHTS

  • who: Ila Joshi et al. from the Fudan University, China have published the paper: Utility of monocyte HLA-DR and rationale for therapeutic GM-CSF in sepsis immunoparalysis, in the Journal: (JOURNAL)
  • future: Nonetheless investigation continues of immunostimulatory agents that aim to reverse CARS effects .

SUMMARY

    Innate immune_responses act rapidly as a first line of defense against invasive, infectious pathogens. (3) Peptide-MHC complexes on antigen presenting cells engage with CD4+ helper T_cells to activate an adaptive immune_response, triggering cytokine release. (4) Activated CD4+ T helper cells undergo clonal expansion, activate . . .

     

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