HIGHLIGHTS
- who: Elise F. Nassif and collaborators from the Washington University in StLouis, United States have published the paper: Case report: Responses to the combination of gemcitabine with sirolimus in two patients with TSC-mutated sarcomas, in the Journal: (JOURNAL)
- what: The authors report on two cases of patients with TSC-mutated sarcomas who experienced significant and prolonged responses to the combination treatment of gemcitabine and sirolimus, after progression on gemcitabine-docetaxel and nab-sirolimus treatments.
SUMMARY
Loss-of-function (LOF) mutations and deletions in Tuberous Sclerosis Complex (TSC) genes result in . . .
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