HIGHLIGHTS
- who: Mohammadreza Kasravi from the Department of Pharmacology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran have published the research: Immunogenicity of decellularized extracellular matrix scaffolds: a bottleneck in tissue engineering and regenerative medicine, in the Journal: (JOURNAL)
- how: This review discusses the interplay between damage-associated molecular patterns (DAMPs) and antigens as the main inducers of innate and adaptive immunity to aid in manufacturing biocompatible grafts with desirable immunogenicity.
- future: Despite data suggesting the release of fragmented ECM components such as elastin and HA as DAMPs upon decellularization the . . .
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