Survivin small molecules inhibitors: recent advances and challenges

HIGHLIGHTS

• who: Najah Albadari and Wei Li from the Department of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee Health Science Center, Memphis, TN, USA have published the research work: Survivin Small Molecules Inhibitors: Recent Advances and Challenges, in the Journal: Molecules 2023, 28, 1376. of /2023/

SUMMARY

All IAP family members have one to three copies of a baculovirus IAP repeat (BIR), a domain with ~70 amino_acids, which is the main mediator of the antiapoptotic function. Structure Cellular of Survivin 142 amino_acid residues. Human survivin has athesignal BIR domain 142proteins amino_acid residues. human . . .

 



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