Cross-linking mass spectrometry for mapping protein complex topologies in situ

HIGHLIGHTS

  • who: Kitaik, Lee and Francis J., O`Reilly from the Center for Structural Biology, Center for Cancer Research, National Cancer Institute (NCI), Frederick, MD, US.A. have published the research: Cross-linking mass spectrometry for mapping protein complex topologies in situ, in the Journal: (JOURNAL) of 03/02/2023
  • what: As we have discussed, while cross-linking MS for purified complexes is an established technology for deriving residue-residue distances, it is a much more difficult proposition to use it to map protein interactions in intact cells.

SUMMARY

    Cross-linking mass . . .

     

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