Dnmt3a-dermatopontin axis suppresses breast cancer malignancy via inactivating yap

HIGHLIGHTS

• who: Danrong Ye from the (UNIVERSITY) have published the article: DNMT3a-dermatopontin axis suppresses breast cancer malignancy via inactivating YAP, in the Journal: (JOURNAL) of 14/08/2022
• how: These in_vitro and in_vivo data showed that DPT serves as a vital antioncogene by inhibiting tumorigenesis in breast cancer. The results showed that the co-expressed genes were significantly enriched in Hippo signaling (P and amplt 0.01 Fig S1e) implying that hippo signaling may be involved in DPTmediated BC suppression. The authors examined YAP activity after DPT overexpression or knockout.
• future: Studies in . . .
  

   

  

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