HIGHLIGHTS
- who: Taj Muhammad et al. from the Pharmacognosy, Department of Pharmaceutical Biosciences, Biomedical Centre, University, Box , have published the article: Transforming Cross-Linked Cyclic Dimers of KR-12 into Stable and Potent Antimicrobial Drug Leads, in the Journal: Biomedicines 2023, 504 of /2023/
- what: To giving further insight into the structure-activity relationship of KR-12 this work shows that by combining peptide stabilization strategies (dimerization backbone cyclization and cross-linking via a disulfide bond) KR-12 can be engineered into a peptide lead with potential utility in a therapeutic context. The aim of this . . .
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