A vector-encoded bispecific killer engager to harness virus-activated nk cells as anti-tumor effectors

HIGHLIGHTS

  • who: Alessia Floerchinger from the (UNIVERSITY) have published the Article: A vector-encoded bispecific killer engager to harness virus-activated NK cells as anti-tumor effectors, in the Journal: (JOURNAL) of 20/01/2023
  • what: This study provides proof-of-concept for MV-BiKE as a novel immunovirotherapy to harness virus-activated NK cells as anti-tumor effectors. The authors report stimulation of human healthy donor NK cells exposed to MV-infected colorectal or pancreatic cancer cells, as indicated by increased CD69 expression compared to mock-infected controls. This study shows that NK cell effector . . .

     

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