Protein kinase c showcases allosteric control: activation of lrrk1

HIGHLIGHTS

  • who: Commentary et al. from the DepartmentUniversity of have published the article: Protein kinase C showcases allosteric control: activation of LRRK1, in the Journal: (JOURNAL) of 10/02/2023
  • how: While in this study PMA was used to activate PKC it would be interesting in future work to determine whether natural agonists of PKC for example activation of phospholipase C through GPCRs also resulted in the phosphorylation and activation of LRRK1.
  • future: It will be interesting to determine in future work whether other Rabs or perhaps other small GTPases are additional substrates to . . .

     

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