Dual blockage of both pd-l1 and cd47 enhances the therapeutic effect of oxaliplatin and folfox in ct-26 mice tumor model

HIGHLIGHTS

• who: Reza Alimohammadi from the DepartmentShahid Beheshti University of have published the research: Dual blockage of both PD-L1 and CD47 enhances the therapeutic effect of oxaliplatin and FOLFOX in CT-26 mice tumor model, in the Journal: Scientific Reports Scientific Reports
• what: Next, the authors aimed to determine whether combining therapy with anti-CD47, anti- PD-L1, and immunological death inducer chemotherapeutic agents (OXP or FOLFOX) could generate antitumor response compared to chemotherapy or bicombinig therapy with chemotherapy and checkpoint blockers. The authors evaluated the potential of combining chemotherapy with blocking both innate and . . .
  

   

  

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