Plakophilin 3 facilitates g1/s phase transition and enhances proliferation by capturing rb protein in the cytoplasm and promoting egfr signaling

HIGHLIGHTS

• who: Lisa Mu00fcller from the Charles Tanford Protein Research Center, Martin Luther UniversityKurt-Mothes-Str A, Halle, Germany have published the research work: Plakophilin 3 facilitates G1/S phase transition and enhances proliferation by capturing RB protein in the cytoplasm and promoting EGFR signaling, in the Journal: (JOURNAL) of January/31,/2023
• what: The authors show that PKP3 stimulates the of ERK and its target RSK1. inhibits expression of the transcription factor RUNX3 a positive regulator of the CDK inhibitor CDKN1A/p21 which is also downregulated by PKP3. The authors describe how PKP3 promotes cell . . .
  

   

  

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