HIGHLIGHTS
- who: EZH and collaborators from the (UNIVERSITY) have published the Article: Process: Submission:03/18/2022 Acceptance:01/22/2023 of Enhancer of Zeste Homolog (EZH2) in, in the Journal: (JOURNAL)
SUMMARY
There are physical and functional links between the epigenetic silencing enzymes DNA methyltransferases (DNMTs), histone deacetylases (HDACs) and EZH2 histone methyltransferase (Tan et_al, 2014; Rinke et_al, 2020). The activity of EZH2 is vital for stem_cell development, including hematopoiesis through its cellular proliferation function. EZH2 dysregulation is strongly oncogenic by directing cells toward a cancer stem_cell (CSC) state and by epigenetic silencing . . .
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