An optimization power calculation approach for precision medicine clinical trials

HIGHLIGHTS

  • who: Peijin, Wang and Shein-Chung, Chow from the Department of Biostatistics and Bioinformatics, Duke University School of Medicine, USA have published the article: An Optimization Power Calculation Approach for Precision Medicine Clinical Trials, in the Journal: (JOURNAL)
  • what: The authors propose an optimization power calculation approach for computing the required sample size for precision medicine clinical trials by controlling variability and maintaining the desired treatment at the same time. The proposed power calculation approach cannot only provide a smaller and more precise sample size for achieving the primary objective of the intended trial but . . .

     

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