HIGHLIGHTS
- who: Qionghong Xie from the DivisionFudan University have published the research: Matrix protein Tenascin-C promotes kidney fibrosis via STAT3 activation in response to tubular injury, in the Journal: (JOURNAL) of 26/08/2022
- what: The study provided strong evidence that TNC played an important role in promoting kidney fibrosis using a TNC knockout mouse line, consistent with a previous study using siRNA-TNC injection approach . The study showed that the TNC-expressing cells (eGFP positive cells) in the fibrotic cortex were primarily localized around the injured tubules that had lost their epithelial markers. The . . .
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