HIGHLIGHTS
- who: Anau00efs Chauvin from the (UNIVERSITY) have published the research: Downregulation of KRAB zinc finger proteins in 5-fluorouracil resistant colorectal cancer cells, in the Journal: (JOURNAL)
- what: The authors investigated intrinsic and acquired resistance to chemotherapy and radiation therapy in CRC cell lines to highlight molecular mechanisms potentially involved in this resistance, and identified proteins from the Kru00fcppel-associated box (KRAB) domain containing zinc-finger proteins (KZFPs) as downregulated in colorectal cancer cell lines that are resistant to 5-FU.
- how: DNA damage assays A time course was carried out to assess . . .
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