Tcf7l2 plays a complex role in human adipose progenitor biology, which might contribute to genetic susceptibility to type 2 diabetes

HIGHLIGHTS

  • who: Manu Verma from the Oxford Centre for Diabetes, Endocrinology and, Radcliffe Department of Medicine, University of Oxford, Oxford , LE, UK have published the article: TCF7L2 plays a complex role in human adipose progenitor biology, which might contribute to genetic susceptibility to type 2 diabetes, in the Journal: (JOURNAL)
  • what: Based on these data the authors focused on deciphering the function of TCF7L2 in APs. The authors demonstrate that TCF7L2 is broadly expressed in AT derived from different fat depots and that its transcript levels are reduced in abdominal AT in obesity.
  • how . . .

     

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