HIGHLIGHTS
- who: Allen L. Hsu from the (UNIVERSITY) have published the paper: Ion Channel Chameleons: Switching Ion Selectivity by Alternative Splicing, in the Journal: (JOURNAL)
- what: In both cases, removal of the charged residue resulted in increased monovalent permeability. re Overall, this study provides new insights into both biophysical and evolutionary mechanisms that determine ion selectivity for voltage-gated channels, a long-standing physiological problem.
SUMMARY
Published na re Voltage-gated sodium and calcium channels are distinct evolutionarily-related ion_channels that achieve remarkable ion selectivity despite sharing an overall similar structure. Classical . . .
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