Disulfiram enhances the antineoplastic activity and sensitivity of murine hepatocellular carcinoma to 5-fu via redox management

HIGHLIGHTS

  • who: Iftekhar Hassan and collaborators from the Department of Zoology, College of Science, King Saud University, Riyadh, Saudi Arabia have published the article: Disulfiram Enhances the Antineoplastic Activity and Sensitivity of Murine Hepatocellular Carcinoma to 5-FU via Redox Management, in the Journal: Pharmaceuticals 2023, 169 of /2023/
  • what: The analysis revealed that reactive oxygen species-mediated oxidative stress is the crucial etiological reason for the pathogenesis of HCC in rats as evidenced by the significantly compromised of major antioxidant enzymes and elevated levels of oxidative damaged products with major histological alterations compared to the . . .

     

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