Berbamine inhibits rankl- and m-csf-mediated osteoclastogenesis and alleviates ovariectomy-induced bone loss

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  • who: NF-u03baB et al. from the Hitchcock, United States Guangzhou University of Chinese have published the Article: Berbamine inhibits RANKL- and M-CSF-mediated osteoclastogenesis and alleviates ovariectomy-induced bone loss, in the Journal: (JOURNAL)
  • what: The authors investigated the effect of BBM on RANKL-induced osteoclast differentiation from bone marrow-derived macrophages (BMMs) in_vitro and ovariectomy (OVX)-induced bone loss in_vivo. Subsequent u00b5CT analysis was conducted to evaluate parameters of the trabecular bone in the distal metaphysis of the femurs using a Scanco u00b5CT-40 scanner (Scanco Medical, Bassersdorf, Switzerland). In the present . . .

     

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