Inhibition of histone deacetylase 6 destabilizes erk phosphorylation and suppresses cancer proliferation via modulation of the tubulin acetylation-grp78 interaction

HIGHLIGHTS

• who: Onsurang Wattanathamsan from the Non-small cell lung cancer , and , cells and normal lung epithelial BEAS- B cells were obtained from the American Type Culture Collection (ATCC have published the paper: Inhibition of histone deacetylase 6 destabilizes ERK phosphorylation and suppresses cancer proliferation via modulation of the tubulin acetylation-GRP78 interaction, in the Journal: (JOURNAL)
• what: In the present study, we, therefore, investigated HDAC6 expression in human lung adenocarcinoma tissues and the underlying mechanism of ERK phosphorylation using the HDAC6 inhibitor trichostatin A (TSA) and small interference to HDAC6 (siHDAC6). The study provides an . . .
  

   

  

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