Case report: precision medicine target revealed by in vitro modeling of relapsed, refractory acute lymphoblastic leukemia from a child with neurofibromatosis

HIGHLIGHTS

  • who: Susan L. Heatley from the Faculty Health and Medical Science, University Adelaide, Adelaide, SA, Australia, Australian and New Zealand Children`s have published the article: Case Report: Precision Medicine Target Revealed by In Vitro Modeling of Relapsed, Refractory Acute Lymphoblastic Leukemia From a Child With Neurofibromatosis, in the Journal: (JOURNAL)
  • what: The authors propose that NF1 p.L2467fs together with the germline NF1 p.L615=caused bi-allelic LOF and therefore contributed to relapse.

SUMMARY

    Neurofibromatosis type 1 (NF-1) is an autosomal dominant disorder that affects approximately 1 in . . .

     

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