African swine fever virus ubiquitin-conjugating enzyme pi215l inhibits ifn-i signaling pathway through stat2 degradation

HIGHLIGHTS

• who: ufeffElenaufeff ufeffRieraufeff and collaborators from the Monash University, Australia have published the research: African swine fever virus ubiquitin-conjugating enzyme pI215L inhibits IFN-I signaling pathway through STAT2 degradation, in the Journal: (JOURNAL)
• what: For the study of ubiquitinated STAT2 in the presence of I215L-WT or I215L-C85A, Vero or COS-1 cells were used. As mentioned above, while many ASFV genes have been described to be involved in the modulation of the IFN-I production by inhibiting the cGAS-STING pathway (reviewed in_(Garcu00eda-Belmonte et_al, 2022)), there are few studies focused . . .
  

   

  

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