C-met-integrin cooperation: mechanisms, tumorigenic effects, and therapeutic relevance

HIGHLIGHTS

  • who: October and collaborators from the Research Center, Greece University, Taiwan have published the research work: c-Met-integrin cooperation: Mechanisms, tumorigenic effects, and therapeutic relevance, in the Journal: (JOURNAL)
  • what: Through carefully analysing the experimental conditions and results of each publication, the authors propose that c-Met-integrin cooperation mainly occurs through the conventional inside-out or outside-in signalling mechanisms. Although here the authors focus on the evidence pertaining to each mode of Frontiers in Cell and Developmental Biology Early studies reported that HGF stimulation of normal and cancer cells increased their adhesion . . .

     

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