Grimace scale, burrowing, and nest building for the assessment of post-surgical pain in mice and rats—a systematic review

HIGHLIGHTS

SUMMARY

The authors identified the following number of papers assessing the pain parameters of interest: 18 papers assessing the Mouse Grimace Scale (MGS), 29 papers assessing the Rat Grimace Scale (RGS), 20 papers assessing nest building in mice, one paper assessing nest building in rats, 10 papers assessing burrowing in mice, and seven papers assessing burrowing in rats. While the number of studies identified per parameter and year tended to increase Type of analgesia in mice (k=39 studies) and rats (k=36 studies) combined for grimace, nest building and burrowing. An influence of the . . .

 



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