Pericyte remodeling is deficient in the aged brain and contributes to impaired capillary flow and structure

HIGHLIGHTS

  • who: Andru00e9e-Anne Berthiaume from the (UNIVERSITY) have published the article: Pericyte remodeling is deficient in the aged brain and contributes to impaired capillary flow and structure, in the Journal: (JOURNAL) of 27/08/2021
  • what: The experiments show that restoration of endothelial coverage following pericyte loss is a synergistic effort from multiple neighboring pericytes, leveraging highly interconnected capillary networks to create access points for remodeling pericytes. The effects the authors report here are based on a restricted scale of pericyte loss, and the authors expect capillary defects to compound with the severity of pericyte . . .

     

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