Monophosphoryl lipid a ameliorates radiation-induced lung injury by promoting the polarization of macrophages to the m1 phenotype

HIGHLIGHTS

  • who: Xingdong Guo from the Department of Radiation Oncology, Chinese PLA General Hospital, Beijing, China have published the research: Monophosphoryl lipid A ameliorates radiation-induced lung injury by promoting the polarization of macrophages to the M1 phenotype, in the Journal: (JOURNAL)
  • what: This study explored the role of_(MPLA) in RILI. The authors demonstrated that MPLA effectively ameliorated radiation injury and inflammation in lung tissues. In the present study, the expression of EMT markers (E-cadherin and vimentin and u03b1-SMA) in the epithelial lung cells were analyzed by immunofluorescence staining. MPLA promoted the proliferation . . .

     

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