Global o-glcnacylation changes impact desmin phosphorylation and its partition toward cytoskeleton in c2c12 skeletal muscle cells differentiated into myotubes

HIGHLIGHTS

• who: Charlotte Claeyssen from the Univ have published the research: Global O-GlcNAcylation changes impact desmin phosphorylation and its partition toward cytoskeleton in C2C12 skeletal muscle cells differentiated into myotubes, in the Journal: Scientific Reports Scientific Reports
• how: As shown on Fig 5b the data indicated that the O-GlcNAcylated desmin was not phosphorylated as no retarded bands were observed after RL-2 immunoprecipitation (Fig 5b left lane) while the authors detected two retarded forms in the whole extract (Fig 5b right lane). To go further in understanding the complex phosphorylation/O-GlcNAcyla- tion interplay . . .
  

   

  

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