Predictive biomarkers of severe immune-related adverse events with immune checkpoint inhibitors: prevention, underlying causes, intensity, and consequences

HIGHLIGHTS

  • who: Ana Cardeu00f1a-Gutieu0301rrez from the Estudios Biosanitarios, Madrid, Spain have published the paper: Predictive Biomarkers of Severe Immune-Related Adverse Events With Immune Checkpoint Inhibitors: Prevention, Underlying Causes, Intensity, and Consequences, in the Journal: Microbiome
  • what: The more promising ones are mentioned in this section, although none of these have been validated yet, and larger prospective studies focusing on this aspect are vital.
  • how: The development of irAEs could be related to the following mechanisms surge in T_cell activity against antigens that are present in tumors and healthy tissue elevation in the . . .

     

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