Adult camk2a gene reinstatement restores the learning and plasticity deficits of camk2a knockout mice

HIGHLIGHTS

  • who: Pomme M.F. Rigter from the of Clinical Genetics, Erasmus Medical Center, GD Rotterdam, the Netherlands have published the article: Adult Camk2a gene reinstatement restores the learning and plasticity deficits of Camk2a knockout mice, in the Journal: (JOURNAL) of November/18,/2022
  • what: The authors show that adult reinstatement of Camk2a rescues all behavioral and electrophysiological phenotypes seen in the Camk2a knockout mice. To conclude, the authors show that CAMK2A expression is required during learning or other types of behavior, independent of its expression throughout development. The authors generated a novel mouse model, allowing . . .

     

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