Research progress of chinese herbal medicine intervention in renal interstitial fibrosis

HIGHLIGHTS

  • who: Interstitial Fibrosis and collaborators from the Department of Nephrology, Shaanxi Provincial Hospital of Traditional Chinese Medicine, Xi`an, China, Department of Northwest University, China have published the research: Research Progress of Chinese Herbal Medicine Intervention in Renal Interstitial Fibrosis, in the Journal: (JOURNAL)
  • what: Using HK2 cells and UUO mice as the research objects, the study showed that novel tetracyclic triterpenoids, namely pachylic acid ZC (PZC), pachylic acid ZD (PZD), and pachylic acid ZE (PZE), could block the overexpression of Wnt/u03b2-catenin signal, thereby intercepting Smad3 phosphorylation and significantly attenuating RIF. Using a . . .

     

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