HIGHLIGHTS
- who: Nishtha Pandey from the for Computational Natural Sciences and Bioinformatics, International Institute of Information Technology, Hyderabad , India have published the research work: Model scenarios for cell cycle re-entry in Alzheimer`s disease, in the Journal: (JOURNAL) of July/15,/2022
- what: The authors show that the integration of multiple feedback loops influences the severity of disease and makes the switch to pathological state irreversible. Based on the model predictions, the authors propose that simultaneous clearance of extracellular Ab aggregates and inhibition of multiple arms of the feedback loop may bring about diseasemodifying effects . . .
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