HIGHLIGHTS
- who: Phillip A. Frankino from the Hughes Medical Institute University of California, Berkeley, CA, USA have published the research: SKN-1 regulates stress resistance downstream of amino catabolism pathways, in the Journal: (JOURNAL) of July/15,/2022
- what: Using a mutant of histidine catabolism as a model, the authors show that this response is independent of canonical MAPK signaling pathways and may partially depend on GCN2 and mTOR homologs gcn-2 and let-363. The authors demonstrate that knockdown of a conserved amidohydrolase in the histidine catabolism pathway leads to a buildup of a catabolite . . .
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