HIGHLIGHTS
- who: Tong Zhang from the National Institutes of Health (NIH), United States Wenzhou Medical University, China have published the research: CMTM6 and CMTM4 as two novel regulators of PD-L1 modulate the tumor microenvironment, in the Journal: (JOURNAL)
- how: Currently most results indicated that CMTM6 helps to establish an immunosuppressive microenvironment in many tumors such as gliomas renal carcinomas and colorectal cancer (CRC) . The GSVA results showed that CMTM6 could promote Treg differentiation and induce T_cell tolerance. Their results indicated that CMTM4 may play a significant role in TME and correlate with the infiltration of . . .
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