HIGHLIGHTS
- who: Jianing Qian and colleagues from the State Key Laboratory of Genetic Engineering, School of Life Science, Fudan University, Shanghai, China have published the article: Mycobacterium tuberculosis PE_PGRS19 Induces Pyroptosis through a Non-Classical Caspase-11/GSDMD Pathway in Macrophages, in the Journal: Microorganisms 2022, 10, 2473. of /2022/
- what: The authors found that a PE_PGRS19 overexpression strain caused an increased further showed that the cell death pyroptosis as the 35 kDa GSDMD release of the cytosolic enzyme LDHtype andwas an increased death ratecleaved of the infected cells. Based on the data , the authors propose . . .
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