Dynamic feedback regulation for efficient membrane protein production using a small rna-based genetic circuit in escherichia coli

HIGHLIGHTS

  • who: Chiara Guidi from the (UNIVERSITY) have published the research work: Dynamic feedback regulation for efficient membrane protein production using a small RNA-based genetic circuit in Escherichia coli, in the Journal: (JOURNAL)
  • what: In this study, a dynamically regulated sRNA-based circuit was developed to counter stress caused by MP production.
  • how: The SohB TMD was selected from a list of different bacterial and human TMDs and signal peptides which were tested for their capacity to guide sfGFP to the E. coli membrane (Additional file 1 Fig S4). Data and statistical analysis . . .

     

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