Su16f inhibits fibrotic scar formation and facilitates axon regeneration and locomotor function recovery after spinal cord injury by blocking the pdgfrβ pathway

HIGHLIGHTS

  • who: Ziyu Li from the Department of Orthopaedics, The Second Hospital of Anhui Medical University, Furong Road, Hefei, Anhui, China have published the research work: SU16f inhibits fibrotic scar formation and facilitates axon regeneration and locomotor function recovery after spinal cord injury by blocking the PDGFRu03b2 pathway, in the Journal: (JOURNAL) of 11/Dec/2021
  • what: The study demonstrates that activation of PDGFRu03b2 pathway can directly induce and specific blocking of this pathway would contribute to the treatment of SCI. The inhibitory microenvironment composed of an inflammatory response in the acute phase and scar tissue . . .

     

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