The bradycardic agent ivabradine acts as an atypical inhibitor of voltage-gated sodium channels

HIGHLIGHTS

  • who: The Bradycardic Agent Ivabradine et al. from the Purdue University Indianapolis have published the research: The Bradycardic Agent Ivabradine Acts as an Atypical Inhibitor of Voltage-Gated Sodium Channels, in the Journal: (JOURNAL)
  • what: Given the diversity of potential future off-label indications for ivabradine, the goal of this study was to investigate the pharmacological action of ivabradine on VGSCs in sufficient detail to gain a better understanding of the pro- and antiarrhythmic effects associated with the administration of this drug. The authors provide additional information regarding the potential molecular basis of the interaction . . .

     

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