Disruption of male fertility-critical dcaf17 dysregulates mouse testis transcriptome

HIGHLIGHTS

  • who: Raed Abu-Dawud from the DepartmentAlfaisal University have published the research work: Disruption of male fertility-critical Dcaf17 dysregulates mouse testis transcriptome, in the Journal: Scientific Reports Scientific Reports
  • what: Dcaf17 is critical for fertility and its mutation causes the Woodhouse-Sakati Syndrome in humans.
  • future: Certainly further studies are required to identify the specific roles of the lncRNAs within the context of the Dcaf17 model and spermatogenesis in general.

SUMMARY

    This perturbed gene_expression profile might be due to aberrant proteolytic and/or non-proteolytic ubiquitination pathway, which . . .

     

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